Thyroid
Science 5(4):CLS1-4, 2010
FDG-PET/CT Visualizes a
Case of Primary Hyperparathyroidism in a
Patient with Gastrointestinal Stromal Tumor
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Laura
Evangelista,1,2 Anna Rita Cervino,1
Michele Gregianin,1 Giorgio Saladini1
1Department of Radiotherapy and Nuclear Medicine Service,
Istituto Oncologico Veneto, Padova, Italy.
2Department of Biomorphological and Functional Sciences,
University Federico II, Napoli, Italy
*Correspondence author:
Laura Evangelista
Istituto Oncologico Veneto, IOV, I.R.C.C.S., Via Gattamelata, 64, 35128
Padova, Italy
Tel: +39 3396687579; Fax: +39 049 821 2205
laura.evangelista@tin.it
Abstract. Background.
Positron emission tomography/computed tomography
(PET/CT) is used in clinical practice above all other tests to define the status
of oncological disease. The predominant use of PET/CT is due to its use of 18F-
fluorodeoxyglucose (FDG) to map cellular glucose metabolism. Some benign
clinical conditions are also detected with FDG-PET/CT. These include
inflammatory or hypermetabolic processes. Parathyroid adenoma is the most common
cause of primary hyperparathyroidism, and nuclear medicine is already used to
locate adenomas and to guide surgery for their removal. The utility of PET/CT
with 11C-methionine for parathyroid disorders is well-documented in the research
literature, while the usefulness of PET/CT with 18F-FDG is not clear. Case
Presentation. We reported a case of a patient without specific symptoms for
primary hyperparathyroidism, with a borderline high value of parathyroid hormone
and a positive finding of parathyroid disease with PET/CT using 18F-FDG.
Conclusion. PET/CT with 18F-FDG is useful in identifying parathyroid adenomas,
and the techniques can be used to precisely clarify the nature of suspected
nodules close to thyroid gland.
Keywords
• Adenoma • Computerized tomography
• 18F-Fluorodeoxyglucose • 11C-Methionine • Oncological disease • Parathyroid
hormone • Parathyroidism • Positron emission tomography
Evangelista, L.,
Cervino, A.R., Gregianin,M., and
Saladini, G.: FDG-PET/CT Visualizes
a case of primary
hyperparathyroidism in a patient
with gastrointestinal stromal tumor.
Thyroid Science, 5(4):1-4,
2010.
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