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  Thyroid Science, 5(2):CR1-3, 2010

Thyrotoxicosis in
Pregnancy Complicated by
Propylthiouracil-induced Hepatitis


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Lajya Devi, MD,1A Rimpy Tandon, MD,2A
Ibha Kumari, MD,2B Anju Huria, MD,2C Poonam Goel, MD2D


 1Department of Obstetrics & Gynecology,
Guru Gobind Singh Medical College, Faridkot, Punjab
1AAssociate professor,
lajja.goyal@rediffmail.com.

2Department of Obstetrics & Gynecology,
Government Medical College & Hospital, Sector–32, Chandigarh
2AAssistant Professor,
drrimpy@yahoo.com;
2B
Ex-Senior Lecturer, kumari.ibha@yahoo.com
;
2CProfessor & Head, anjuhuria@yahoo.com;
2D
Professor, poonam1302@yahoo.com

*Corresponding Author: Dr. Rimpy Tandon,
Assistant Professor, Department of Obstetrics & Gynecology,
Government Medical College & Hospital, Sector-32,
Chandigarh,
drrimpy@yahoo.com

Abstract. Graves’ disease is the most common cause of hyperthyroidism during pregnancy. Propylthiouracil (PTU) is the treatment of choice due to its relative safety during pregnancy compared to methimazole. However, rarely, PTU causes serious complications like hepatitis. We report a case of hepatitis possibly related to PTU during pregnancy complicated by thyrotoxicosis.

Keywords • Graves’ disease • Hepatitis • Methimazole • Pregnancy • Propylthiouracil • Thyrotoxicosis

Devi, L., Tandon, R., Kumari, I., Huria, A., and Goel, P.: Thyrotoxicosis in Pregnancy Complicated by Propylthiouracil-induced Hepatitis. Thyroid Science 5(2):CR1-3, 2010.

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© 2010 Thyroid Science